Biomarker research and metabolic profiling in IEMs and vitamin B deficiencies

Our group has strong experience in method development for the determination of metabolites in body fluids using chromatography and mass spectrometry techniques. We are particularly interested in the detection, quantification and interpretation of biomarkers for inborn errors of metabolism (IEMs) and nutritional status.



  • Energy metabolites in cell compartments (Prof. J-M Nuoffer)
  • Metabolic profiling in MDH2-deficient iPSCs (PD Dr. med. A. Lämmle)
  • Metabolic profiling in galactosemia (Dr. med. M. Gautschi)
  • Fatty acids quantification in mouse retina (Dr. phil. nat. B. Steiner, Prof. P. Escher)
  • Metabolism of Echinococcusmultilocularis (Prof. B. Lundström-Stadelmann, Vetsuisse)